Why do antibiotics cause clostridium difficile




















Having diarrhoea while taking antibiotics does not necessarily mean you have C. Diarrhoea can be caused by a number of conditions and is a common side effect of antibiotics.

A blood test may also be needed to help determine how severe the infection is. Sometimes you may need other tests or scans in hospital to check if your bowel is damaged. Your GP will advise if you need hospital treatment if you're not already in hospital.

If you're in hospital, you might be moved to a room of your own during treatment to reduce the risk of the infection spreading to others. But the symptoms come back in around 1 in 5 cases and treatment may need to be repeated. If you're well enough to recover from Clostridium difficile C. Your GP may contact you regularly to make sure you're getting better.

Diff, and not everyone has the same risk. Although almost any antibiotic can cause it, the worst culprit, in this case, is often broad-spectrum antibiotics. Those most at risk are patients 65 or older who have been in a healthcare setting, such as a hospital or nursing home.

Erika Prouty, Pharm. Both Dr. Akselrod and Dr. Prouty identify clindamycin and fluoroquinolones as some of the worst offenders. The list of antibiotics that could cause C. Diff includes:. These drugs include:. But as a medical professional immersed in this field, she is well-aware of the fine line physicians must walk in terms of both treating the illness at hand, while not introducing additional infection. What is Clostridium difficile C. Symptoms of C. Mild symptoms can include: Watery diarrhea 3 or more times each day for several days.

Stomach pain or tenderness. Severe symptoms can include: Frequent, watery diarrhea up to 15 times each day. Severe stomach pain or tenderness. Call your doctor if: Symptoms begin after taking an antibiotic.

Symptoms last longer than 3 days or get worse. What causes a C. Other risk factors include: Surgery of the gastrointestinal GI tract. Stomach surgery that requires moving the intestines aside. A stay in the hospital. Living in a nursing home or extended-care facility.

Colon problems, such as inflammatory bowel syndrome IBS or colorectal cancer. Weakened immune system. Prior C. If you are in good health, you likely will not get a C. How is C. Can a C. Wash your hands often and well, using soap and water. Use disposable gloves when caring for someone who may have C. Use chlorine bleach-based products to disinfect surfaces and items. Wash clothing that may be soiled with stool with soap and chlorine bleach. If you visit someone in a health care facility, wash your hands before, during, and after your visit.

To help prevent the spread of C. If you have a friend or family member in a hospital or nursing home, follow recommended practices. Ask questions if you observe caregivers or other people not following guidelines. Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. This content does not have an English version. This content does not have an Arabic version.

Sections for C. Email address. First Name let us know your preferred name. Last Name. Thank you for subscribing Your in-depth digestive health guide will be in your inbox shortly. Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry. Request an Appointment at Mayo Clinic. Colon and rectum Open pop-up dialog box Close. Colon and rectum The colon, also called the large intestine, is a long, tube-like organ in your abdomen.

Share on: Facebook Twitter. Show references Clostridioides formerly Clostridium difficile-induced diarrhea. Merck Manual Professional Version. Accessed May 24, LaMont JT. Clostridium difficile in adults: Epidemiology, microbiology, and pathophysiology. Frequently asked questions about Clostridium difficile for healthcare providers. Centers for Disease Control and Prevention.

Guh AY, et al. Trends in U. New England Journal of Medicine.



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